Why At-Home Blood Tests?
At-home blood testing has exploded from a niche biohacker tool into a mainstream longevity category. Services like Function Health, InsideTracker, and Superpower promise 100+ biomarkers from a single draw — but “100 biomarkers” means wildly different things depending on the provider. Some count calculated ratios as separate markers; others bundle add-on panels that cost extra. The category’s biggest controversy — Function Health’s 2026 lawsuit against Superpower over deceptive biomarker-count marketing — proves the comparison gap is real.
What We Compare
Every service in our comparison is evaluated on:
- Normalized biomarker coverage — we count unique measured analytes, not calculated ratios or marketing bundles. A 100-biomarker claim that includes 30 calculated ratios is reported as 70 measured markers.
- Cost-per-biomarker — total annual membership ÷ unique measured analytes. The single most useful number for value comparison.
- CLIA/CAP lab partner status — which reference lab processes the samples, and whether they hold both CLIA certification and CAP accreditation (the gold standard for US clinical labs).
- Biological age / longevity scoring — which services offer epigenetic or multi-marker biological age estimates, and what the methodology is.
- Actionable reporting — do results come with clinician interpretation, AI-generated recommendations, or raw data only?
Key Findings (2026)
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Function Health ($499/yr) offers the densest panel at 110+ measured biomarkers per draw, with Quest Diagnostics as the CLIA/CAP lab partner. Cost-per-biomarker is among the lowest in the category at ~$2.30/marker/draw.
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Superpower’s “100+ tests” marketing is under legal challenge. Function Health alleges deceptive counting. We independently verified that Superpower’s standard panel measures ~65 unique analytes with several calculated ratios counted as separate tests.
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InsideTracker remains the best for actionable recommendations — its InnerAge 2.0 biological age model and food/supplement/exercise prescription engine are unmatched. But at $589/yr for the Ultimate plan with fewer markers than Function, value-per-biomarker is lower.
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Finger-prick services (Everlywell, LetsGetChecked) serve a different audience — fewer markers, faster results, lower commitment. Not comparable to full-panel longevity services but valid for targeted screening.
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No service is a substitute for physician-ordered bloodwork. All at-home services use the same CLIA-certified labs as your doctor, but interpretation depth varies. SiPhox and Lifeforce include clinician consults; Function and Superpower do not.
Who Should Read This
- Biohackers tracking biomarkers quarterly for longevity optimization
- Anyone comparing Function Health vs Superpower vs InsideTracker
- People who want bloodwork without a doctor’s visit
- Buyers who want to understand what “100 biomarkers” actually means