NOVOS Core
Bundles 12 longevity-research compounds into one daily dissolvable sachet, with a published ingredient rationale — a convenience play, not a proven anti-aging drug
NOT CLEARED
No FDA clearance, registration, or CE marking found.
Key facts at a glance.
- Founded
- 2019
- Headquarters
- New York City, USA
- Price range
- $79–$109
The real price over three years.
Total cost of ownership · 3yr
| Hardwareone-time | $79 |
| 3-year total | $79 |
What the device does.
- + 12-compound formula (Ca-AKG, fisetin, pterostilbene, glycine, glucosamine sulfate, magnesium malate, L-theanine, rhodiola, ginger, hyaluronic acid, vitamin C, micro-dosed lithium)
- + Daily dissolvable powder sachet, ~6.9 g total actives per serving
- + Three flavour options (Orange, Tropical Passion, Unflavoured)
- + Brand states the formula is third-party tested
- + Subscription pricing lowers the per-box cost
The trade-offs.
- + One sachet bundles 12 longevity-research compounds (Ca-AKG, fisetin, pterostilbene, glycine, glucosamine and more) that people otherwise buy separately
- + Daily powder format with three flavour options — no pill-stacking
- + Brand states the formula is third-party tested and publishes its ingredient rationale
- + Subscription pricing brings the per-box cost down to about $79
- − Per-ingredient doses are not publicly disclosed, so you cannot verify amounts against the clinical literature
- − The headline efficacy evidence is a small, brand-funded human pilot plus animal data — not independent randomised trials
- − Premium price versus buying the handful of evidence-backed ingredients on their own
- − Some users report temporary stomach discomfort
Longevity-focused users who want one multi-ingredient daily formula instead of stacking single supplements
The long read.
§ Hands-on instrument testing pending. Based on published specifications and third-party data.
Overview
NOVOS Core is a daily dietary supplement from NOVOS Labs (New York, founded 2019) that packs 12 separate compounds into one dissolvable powder sachet — roughly 6.9 g of actives per serving. The pitch is convenience: instead of buying and dosing calcium alpha-ketoglutarate, fisetin, pterostilbene, glycine and the rest individually, you get them in a single drink.
Read this for what it is. NOVOS Core is a supplement, not a drug. Nothing here treats, prevents or cures disease, and no supplement has been shown to extend human lifespan. This review covers what the product contains, what’s actually disclosed, and how strong the evidence behind it is.
What’s in it — and what isn’t disclosed
The 12 compounds are calcium alpha-ketoglutarate (Ca-AKG), fisetin, pterostilbene, glucosamine sulfate, glycine, magnesium malate, L-theanine, rhodiola rosea, ginger extract, hyaluronic acid, vitamin C and a micro-dose of lithium. Several of these have a genuine research base for general healthy-aging mechanisms — Ca-AKG, glycine and fisetin in particular are active areas of study.
The key limitation is transparency: NOVOS discloses the total active weight (~6.9 g) but not the amount of each ingredient. That matters, because for compounds like Ca-AKG the dose used in research is substantial, and without a label breakdown you cannot tell whether Core delivers a research-relevant amount or a token sprinkle. We treat undisclosed dosing as a real drawback, not a footnote.
The evidence, honestly
NOVOS cites an in-house-funded mouse study (run at a university lab) reporting a lifespan increase in aged mice, plus a small human pilot looking at epigenetic-aging markers. Take both at face value: animal and in-vitro results do not transfer to human lifespan, and a small, brand-funded pilot is a starting point, not proof. There are no large, independent randomised controlled trials demonstrating that NOVOS Core slows aging in people. Anyone selling that conclusion is ahead of the data.
Cost
About $109 for a one-time box (30 sachets), dropping to roughly $79/box on the annual subscription. That’s premium pricing for a supplement — justified mainly by the breadth of the formula, not by proven outcomes.
Regulatory status
NOVOS Core is a dietary supplement regulated under the US DSHEA framework. It is not evaluated by the FDA, and the label carries the standard disclaimer that it is not intended to diagnose, treat, cure or prevent any disease. The brand states the product is third-party tested but does not name the certifying body on the product page; if independent purity testing matters to you, ask NOVOS for the certificate of analysis.
Where it fits
- Consider it if you want one convenient daily formula spanning several longevity-research ingredients and you accept both the dosing opacity and the premium price.
- Skip it if you prefer to dose a few evidence-backed ingredients yourself at known amounts — that route is cheaper and fully transparent.
Verdict: Not yet tested
We have not independently tested NOVOS Core or lab-verified its contents, so we are not assigning a recommendation. As a convenience product it’s a reasonable, well-formulated option; as a longevity product its real-world benefit is unproven. Buy it for the convenience and the mechanism-level rationale — not for any promise about your lifespan.
How we’ll assess it
If we cover this category hands-on, we will request a certificate of analysis, compare disclosed amounts against published research doses, and report tolerability over a multi-week trial. See our methodology.
Changelog
- 2026-06-16: Initial listing. Not yet tested; structure-function framing only.
What we'll measure on the bench.
- Protocol
- Third-party purity assay (NSF / USP)
- Primary metric
- Active compound % vs label claim
- Pass threshold
- within ±10% of label · contaminants below FDA limits
- Session shape
- 3 bottles from 3 channels, paired assay
§ Bench session pending. Measured values will replace this panel as the protocol completes — see Plate VI · Methodology for the full testing rulebook.
Common questions.
- How much does NOVOS Core cost?
- NOVOS Core costs $79–$109.
- Does NOVOS Core require a subscription?
- No. NOVOS Core does not require a subscription — there is no mandatory recurring fee to keep using it.