myDNAge (Epimorphy)
One of the few tests based directly on Horvath's original clock — the most-cited epigenetic age algorithm; unique urine sample option
NOT CLEARED
No FDA clearance, registration, or CE marking found.
Key facts at a glance.
- Founded
- 2017
- Headquarters
- Costa Mesa, CA, US
- Price range
- $299–$299
The real price over three years.
Total cost of ownership · 3yr
| Hardwareone-time | $299 |
| 3-year total | $299 |
What the device does.
- + Based on the original Horvath Clock (gold-standard 1st-gen epigenetic clock)
- + Proprietary SWARM technology analyzing 2,000+ methylation loci
- + Accepts blood or urine samples
- + Simple single-number biological age result
- + 4-6 week turnaround
- + Ships to US, Canada, Europe, Australia
The trade-offs.
- + **Based on the original Horvath Clock** — most-cited 1st-generation epigenetic age algorithm in research literature
- + Proprietary SWARM technology analyzing 2,000+ methylation loci
- + **Unique urine sample option** — only consumer bio-age test offering urine-based methodology
- + $299 mid-tier accessible pricing
- + Ships to US, Canada, Europe, Australia
- − **1st-generation clock only** — no DunedinPACE, no organ-system breakdown vs TruDiagnostic / Elysium / Generation Lab
- − Minimal reporting — just biological age number without deep lifestyle recommendations
- − Amazon rating only 3.7/5 (13 reviews) with very limited online presence
- − No physician consultation or personalized action plan included
- − Slower 4-6 week turnaround (matched only by Elysium's 6 weeks)
Budget-conscious consumers wanting a straightforward biological age number, researchers familiar with the Horvath clock
The long read.
§ Hands-on instrument testing pending. Based on published specifications and third-party data.
Overview
myDNAge (Epimorphy) is the original Horvath Clock methodology specialist in consumer bio-age testing — manufactured by Epimorphy (founded 2017 in Costa Mesa CA), with structural credibility differentiator being direct implementation of Steve Horvath’s original epigenetic clock (the most-cited 1st-generation epigenetic age algorithm in aging research literature). Unique consumer-market feature: urine sample option — only consumer bio-age test offering urine-based methodology vs blood (TruDiagnostic, Generation Lab) or saliva (Elysium) or cheek-swab (Tally Health) alternatives.
The structural value claim is genuine for Horvath-Clock-aligned users: the original Horvath Clock published 2013 remains the most-cited epigenetic clock methodology in aging research. myDNAge’s proprietary SWARM technology analyzing 2,000+ methylation loci provides faithful Horvath-methodology implementation. $299 mid-tier accessible pricing matches Elysium Index. International shipping (US, Canada, Europe, Australia) provides broader geographic accessibility than US-only competitors.
The structural editorial caveats are significant: 1st-generation clock only means no DunedinPACE (3rd-generation Pace of Aging clock), no organ-system breakdown (vs TruDiagnostic’s 11 / Elysium’s 9 / Generation Lab’s 19), and no multi-clock approach (TruDiagnostic uses OMICmAge + SYMPHONYAge + DunedinPACE). Minimal reporting delivers just biological age number without lifestyle recommendations. Amazon rating 3.7/5 from only 13 reviews + very limited online presence reflects mid-tier consumer adoption. No physician consultation or action plan included. Slower 4-6 week turnaround matches Elysium but lags TruDiagnostic / GlycanAge / NOVOS at 3-4 weeks.
For users specifically wanting Horvath-Clock methodology + urine-sample option, myDNAge is structurally distinctive. For users wanting modern multi-clock methodology, organ-system breakdown, or comprehensive lifestyle recommendations, alternatives are structurally better matched.
When myDNAge Makes Sense
Strong fit: Researchers familiar with Horvath Clock wanting consumer-accessible Horvath methodology; users with blood-draw aversion wanting urine alternative; international buyers (US/Canada/Europe/Australia shipping); minimalist single-number-result preference.
Weaker fit: Multi-clock methodology preference (TruDiagnostic); organ-system breakdown needs (Generation Lab 19, TruDiagnostic 11, Elysium 9); comprehensive lifestyle recommendations; faster turnaround (3-4 weeks via TruDiagnostic / GlycanAge / NOVOS); strong consumer-experience signal.
3-Year Cost of Ownership
| Use case | Cost |
|---|---|
| myDNAge single test | ~$299 |
| Annual retest | ~$897 / 3 yr |
| 3-year ownership | ~$300-900 |
Compare: TruDiagnostic ($399-799), Elysium Index ($299 saliva), GlycanAge ($348 glycan), Tally Health ($229 cheek swab), Generation Lab ($490-500), NOVOS Age ($349), Viome ($129-399 multi-omic).
Verdict: Conditional
myDNAge (Epimorphy) earns a conditional verdict on the strength of its direct implementation of original Horvath Clock methodology (most-cited 1st-generation epigenetic age algorithm in research literature), proprietary SWARM technology analyzing 2,000+ methylation loci, unique urine sample option (only consumer bio-age test with urine methodology), $299 mid-tier accessible pricing, and international shipping (US/Canada/Europe/Australia) — balanced against 1st-generation clock only without DunedinPACE or organ-system breakdown, minimal reporting (single number without recommendations), Amazon rating 3.7/5 with only 13 reviews, no physician consultation or action plan, and 4-6 week turnaround.
For Horvath-Clock-aligned researchers and users wanting urine-based bio-age methodology, myDNAge is structurally distinctive. For modern multi-clock methodology, organ-system breakdown, comprehensive recommendations, or stronger consumer-experience signal, alternatives are structurally better matched.
Changelog
- 2026-05-07: Initial review published based on myDNAge (Epimorphy) published specifications, Horvath Clock methodology positioning, urine sample option documentation, and aggregated user-report data.
What we'll measure on the bench.
- Protocol
- Methodology audit + 3-month paired retest
- Primary metric
- Δ biological age between paired tests
- Pass threshold
- <±2 yr drift across stable-lifestyle window
- Session shape
- 2 paired tests, 3 months apart
§ Bench session pending. Measured values will replace this panel as the protocol completes — see Plate VI · Methodology for the full testing rulebook.